This is such cool info about the Metformin. And your tag of "the incredible shrinking woman" was kind of nostalgic for me because back before I had such trouble with my feet and I was going to yoga three times a week, my yoga instructor called me her "ISW". I'm still waiting on Metformin to work it's magic on me, and it has...in some ways, like my cholesterol, but not in poundage yet. I'm on 1000mg/day, how about you?